A Comparison of Three Nutritional Assessment Methods Predicting Prognosis in COPD With Respiratory Failure

Pulmonary Disease, Chronic Obstructive Clinical Trial

Official title:

Prediction of Prognosis in Patients With Chronic Obstructive Pulmonary Disease With Respiratory Failure: A Comparison of Three Nutritional Assessment Methods

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02942784
• Other study ID #: COPD-001
• Status: Completed
• Start date: April 1, 2017
• Est. completion date: May 12, 2017

Study information

• Verified date: December 2019
• Source: West China Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This is a retrospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during January 2014 to March 2016 by review of medical records. The following variables will be retrospectively studied: age, sex, marriage, height, weight, respiratory rate, PaO2, PaCO2, nutritional risk screening 2002 (NRS 2002) score, ALB, short-term and long-term prognostic outcomes, and so on. The purpose of this study is to compare the predictive power of three widely used nutritional assessment methods (BMI, NRS 2002 and ALB) predicting the prognostic outcomes in a cohort of COPD patients with respiratory failure.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 750
• Est. completion date: May 12, 2017
• Est. primary completion date: May 12, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Newly diagnosis of COPD at West China Hospital during January 2014 to March 2016

• Partial pressure of O2 (PaO2) < 60 mmHg and/or partial pressure of CO2 (PaCO2) >50 mmHg

• Age = 18 years

• Respiratory rates > 23 bpm

Exclusion Criteria:

• Pregnancy or during lactation

• Ventilatory dysfunction due to neuromuscular disorders, acute and chronic thromboembolic disease, severe illness in other systems

• Incomplete medical profiles

Related Conditions & MeSH terms

• Lung Diseases
• Pulmonary Disease, Chronic Obstructive
• Pulmonary Valve Insufficiency
• Respiratory Insufficiency

Locations

Country	Name	City	State
China	West China Hospital	Chengdu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
West China Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of in-hospital death		up to 27 months
Primary	Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 1-year death after discharge		up to 27 months
Primary	Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 30-day readmission after discharge		up to 27 months
Secondary	Collection of Demographics (age, sex, marriage)		up to 27 months
Secondary	Number of participants with in-hospital death		up to 27 months
Secondary	Number of participants with 1-year death after discharge		up to 27 months
Secondary	Number of participants with 30-day readmission after discharge		up to 27 months