Cerebrospinal Fluid IL-6, IL-8 and PCT as Early Marker of an Intrathecal Infection in Neurosurgical Patients

External Ventricular Drainage Associated Infection Clinical Trial

Official title:

Early Detection of CSF Infection in Neurosurgical Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02875808
• Other study ID #: CSF IL-6, IL-8 and PCT
• Status: Completed
• Start date: August 1, 2014
• Est. completion date: December 12, 2017

Study information

• Verified date: November 2018
• Source: University Medicine Greifswald
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The value of CSF IL-6, IL-8 and Procalcitonin in detecting an early diagnosis of intrathecal infection in neurosurgical patients with an external ventricular drainage is evaluated.

Description:

The value of CSF IL-6, IL-8 and Procalcitonin in detecting an early diagnosis of intrathecal infection in neurosurgical patients with an external ventricular drainage is evaluated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: December 12, 2017
• Est. primary completion date: September 1, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• external ventricular drainage

• informed consent

Exclusion Criteria:

• no informed consent

• prior intrathecal infection

• prior systemic infection / sepsis

Related Conditions & MeSH terms

• Communicable Diseases
• External Ventricular Drainage Associated Infection
• Infection
• Intrathecal Infection

Locations

Country	Name	City	State
Germany	Department of Neurosurgery	Greifswald

Sponsors (1)

Lead Sponsor	Collaborator
University Medicine Greifswald

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	increasing IL-6, IL-8 and PCT prior to an clinically apparent intrathecal infection/ a detection with the goldstandard		08/ 2014 - 12/ 2016