Wound Infection and Wound Healing Clinical Trial
Official title:
The Effect of L-PRP on Wound Healing and Wound Infection After Pancreaticoduodenectomy / Whipples Surgery
The purpose of this project is to investigate whether a combination of a local injection of
platelet rich plasma (PRP) combined with a daily supplement of vitamin C, zinc, L-arginine,
as well as high protein diet (1.5 g of protein per kilo body weight per day) can promote
tissue healing in patients undergoing open upper-abdominal surgery.
Primary endpoint is cases of wound infection and secondary endpoints are time of tissue
regeneration (days), judged by traditional clinical observation and experimentally assessed
by ultrasound.
The experiment is performed as a parallel two-armed, randomized, controlled trial.
A total of 40 subjects will be included in the trial i order to ensure the power of the
study, despite a drop off of up to 25%.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention