Comparison of Walking in Water and on Land in People With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive Clinical Trial

Official title:

Determining the Metabolic Load of Walking in Water Compared to Walking on Land in People With COPD, Who Are Normal Weight and Obese, Compared to Peak Exercise Metabolic Response: a Prospective, Randomised Cross-over Pilot Trial

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02757157
• Other study ID #: ERS STRTF 2015 - 9368
• Status: Terminated
• Phase: N/A
• Start date: October 2016
• Est. completion date: January 1, 2020

Study information

• Verified date: August 2021
• Source: European Respiratory Society
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the metabolic load during a single session of moderate intensity walking in water compared to walking on land (over-ground) in people with chronic obstructive pulmonary disease (COPD) who are normal weight and obese, compared with peak exercise metabolic response. The hypothesis is that the metabolic load of walking at a moderate intensity in water will be greater than walking on land.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 14
• Est. completion date: January 1, 2020
• Est. primary completion date: January 1, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• diagnosis of COPD (FEV1/FVC <0.7) in a clinically stable state (no acute exacerbation of COPD within the previous 4 weeks)
• accepting of walking in water
• BMI >/= 21 kg/m2

Exclusion Criteria:

• long-term oxygen therapy
• contraindications to entering a hydrotherapy pool

Related Conditions & MeSH terms

• Lung Diseases
• Pulmonary Disease, Chronic Obstructive

Intervention

Behavioral:
• Water-based walking
Participants will walk in the water for 15 minutes at an intensity rating of five on the modified Borg scale for dyspnoea or perceived exertion, whichever is the highest. Walking intensity will be measured every three minutes during each walking session. If the intensity level is reported as below five, participants will be encouraged to increase the intensity by increasing their walking speed. During walking in water, VO2 and VE will be measured breath-by-breath using the Oxycon mobile. Every three minutes during the walking, heart rate, oxygen saturation, dyspnoea and exertion will be measured.
• Land-based walking
Participants will walk on land for 15 minutes at an intensity rating of five on the modified Borg scale for dyspnoea or perceived exertion, whichever is the highest. Walking intensity will be measured every three minutes during each walking session. If the intensity level is reported as below five, participants will be encouraged to increase the intensity by increasing their walking speed. During walking on land, VO2 and VE will be measured breath-by-breath using the Oxycon mobile. Every three minutes during the walking, heart rate, oxygen saturation, dyspnoea and exertion will be measured.

Locations

Country	Name	City	State
Netherlands	Centre of intergrated rehabilitation for chronic organ failure	Horn

Sponsors (2)

Lead Sponsor	Collaborator
European Respiratory Society	Center for Integrated Rehabilitation and Organ Failure Horn

Country where clinical trial is conducted

Netherlands, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Dyspnoea, measured by the modified Borg 0-10 category ratio scale		Day of assessment during study measurement period (15 minutes)
Other	Exertion, measured by the modified Borg 0-10 category ratio scale		Day of assessment during study measurement period (15 minutes)
Other	Oxygen saturation		Day of assessment during study measurement period (15 minutes)
Other	Heart rate		Day of assessment during study measurement period (15 minutes)
Primary	Breath-by-breath oxygen consumption (VO2)		Day of assessment during study measurement period (15 minutes)
Secondary	Minute ventilation (VE)		Day of assessment during study measurement period (15 minutes)