Multi-drug Resistant Gram-negative Bacilli Colonization Clinical Trial
Official title:
IGHID 11519 - Multidrug Resistant Gram-negative Bacilli Colonization and Infection in Burn
This is a prospective observational study to determine the role of colonization and identify the timing of development of drug resistance in multidrug resistant Gram-negative bacilli (MDR-GNB) causing infection among critically ill burn patients.
This is a prospective observational study. Patients will be followed during a single
admission for development of colonization or infection with MDR-GNB. Patient clinical
characteristics, including infections, surgeries, and antibiotic exposure, will be collected
in real-time.
Weekly surveillance wound and peri-rectal swabs and, if intubated, biweekly deep endotracheal
or tracheostomy aspirates will be collected, de-identified, and stored from all patients and
examined for the presence of MDR-GNB. All GNB isolates from blood, urine, respiratory, and
wound cultures will be collected, coded, and stored.
;