Preoperative Screen for Substance Abuse in in Patients Undergoing Emergency Operation Clinical Trial
Official title:
Preoperative Screen for Substance Abuse in Trauma Patients Undergoing Emergency Operation: a Prospective Observational Study
| Verified date | April 2017 |
| Source | West China Hospital |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
Substance abuse is a growing problem world wide, and treatment of substance abusers in the perioperative period, especially for emergency operation is challenging. The objectives of this study are to determine the proportions of substance abusers in the trauma patients undergoing emergency operation by preoperative screen, observe the differences of consumption of anesthetics and other medications during perioperative period between substance abusers and non-abusers, as well as postoperative complications, and explore an optimal scheme for substance abusers.
| Status | Completed |
| Enrollment | 1031 |
| Est. completion date | March 2017 |
| Est. primary completion date | December 2016 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 16 Years to 70 Years |
| Eligibility |
Inclusion Criteria: - Patients aged 16~70 years; - Informed consent signed Exclusion Criteria: - Aged<16 years or >70 years; - Refuse to sign consent; - Other conditions that may preclude the patients from the study, such as language barrier, psychiatric disorders, unable to attend research center for follow up. - Patients who enrolled to another research study or are taking experimental medication in last 3 months prior to this study. - Not suitable for the study, after assessment by the investigators. |
| Country | Name | City | State |
|---|---|---|---|
| China | West China Hospital, Sichuan University | Chengdu | Sichuan |
| Lead Sponsor | Collaborator |
|---|---|
| West China Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Other | Proportion of HIV, HCV, syphilis positive in substance abusers and non-abusers. | 1 day | ||
| Primary | Proportion of substance abuser in all the emergency operation patients | The proportion will be calculated as the number of substance abusers / total number of enrolled calculated as the number of substance abusers / total number of enrolled patients | 1 year | |
| Secondary | Perioperative consumption of medications | Perioperative consumption of sulfentanil, midazolam, propofol, and muscle relaxant in substance abusers and non-abusers. | 1 day | |
| Secondary | Incidence and severity of postoperative complications | 30 days |