Other Clinical Trial - Transdermal Vagal Stimulation for POTS

Status Active, not recruiting

Clinical Trial Summary

Some patients experience high heart rates and symptoms of light-headedness, fatigue, headache during standing despite well maintained blood pressure. These patient are disabled and can't be in upright position for a longer time. The purpose of this study is to test whether electrical stimulation of a nerve through a skin of the ear may improve heart rate response and reduce disabling symptoms.

Clinical Trial Description

Background Postural Tachycardia Syndrome (POTS) is a syndrome characterized by disabling symptoms of inadequate cerebral perfusion on assuming the upright posture, including light-headedness, fatigue, palpitations, altered mentation, headache, nausea, presyncope, and occasionally syncope. POTS is characterized by an excessive increase in heart rate and exaggerated increase in plasma catecholamine levels on standing in the absence of a blood pressure fall. These disabling symptoms persist for more than six months. Objective The objective of this study is to study the effect of vagal stimulation on heart rate modulation during supine and upright posture as a treatment modality for patients with POTS. ;

Study Design

Related Conditions & MeSH terms

Postural Orthostatic Tachycardia Syndrome
Syndrome
Tachycardia

Clinical Trial Details

NCT number	NCT02281097
Study type	Interventional
Source	Vanderbilt University Medical Center
Contact
Status	Active, not recruiting
Phase	N/A
Start date	June 2013
Completion date	December 2025

View Details

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