Adenoma Detection Rate Improvement in Screening Colonoscopy Clinical Trial
Official title:
Endoscopic Size Assessment of Advanced Adenomatous Polyps; Inter Observer Variations
| NCT number | NCT02193646 |
| Other study ID # | ESA-2014 |
| Secondary ID | |
| Status | Recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | November 2010 |
| Est. completion date | January 2026 |
The investigators are retrospectively comparing detection rates of adenomatous polyps, advanced adenomas, and size assessment of the polyps among Rush University Medical Center endoscopists. The investigators plan to review whether the size assessment of adenomatous polyps affected the surveillance protocols and if the location of polyps detected affected the detection rates.
| Status | Recruiting |
| Enrollment | 5000 |
| Est. completion date | January 2026 |
| Est. primary completion date | January 2026 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 40 Years to 80 Years |
| Eligibility | Inclusion Criteria: - Presence of adenomatous polyps detected at endoscopy and diagnosed pathologically by tissue biopsy - Have a colonoscopy at RUMC for screening purposes Exclusion Criteria: - Failure to meet inclusion criteria - Previous diagnosis of IBD or colorectal cancer |
| Country | Name | City | State |
|---|---|---|---|
| United States | Amanda Lin | Chicago | Illinois |
| Lead Sponsor | Collaborator |
|---|---|
| Rush University Medical Center |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Adenomatous Polyp Detection Rate | Assessing for advanced adenomas (including location). | one year | |
| Primary | Endoscopic Size Assessment Versus Pathological Size Assessment | Size of polyps at time of endoscopic procedure will be compared to the size of the same polyp by pathological assessment. | one year | |
| Secondary | Retroflexion as an indication of adenoma detection rate in colorectal cancer screening | Retroflexion is a common but not mandatory practice in colonoscopy which as not been systematically studied in terms of polyp detection. Charts will be reviewed to determine whether retroflexion was performed. | one year |