Head and Neck Squamous Cell Carcinoma Clinical Trial
Official title:
An Epidemiological Study of Mucosal Squamous Cell Carcinomas of the Head and Neck
This study is designed to refine the aetiological causes of cancers of the head and neck and
investigate the ways in which human papillomavirus and life-style factors cause head and
neck cancers. This study will determine if these factors affect the treatment of cancer.
All patients attending the Head and Neck Clinic at the Princess Alexandra Hospital is
invited to complete a risk factor questionnaire and give consent for their clinical data and
tissue samples to be available for future research activities. The risk factor questionnaire
is based on existing validated instruments developed by the QIMR Berghofer Medical Research
Institute Cancer Control Group, and will collect standardised information relating to
demographics and causal factors (tobacco and alcohol intake), risk modifiers (dentition,
asprin and non-steroidal anti-inflammatory drugs (NSAIDS), height, weight, physical
activity, diet quality etc) and behaviours (oral sex etc)
Data is collected using a simple four-page paper-based questionnaire. Information to be
collected include age, sex, height and weight (at age 20, current age, and heaviest ever),
history of cancer (own and partner). Questions about recreational physical activity, smoking
history and alcohol consumption, acid reflux, heartburn, denture use and tonsillectomy,
frequency of use of paracetamol, antihistamine and NSAIDS.
The questionnaires also ask participants some detailed questions about sexual behaviour and
history if they are comfortable to give this information.
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Observational Model: Case Control
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