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Clinical Trial Summary

Radical prostatectomy is the most common and effective treatment for localized prostate cancer. Unfortunately, radical prostatectomy is associated with significant adverse effects, such as urinary incontinence, sexual dysfunction, and reduced physical function that collectively diminish health-related quality of life which may persist for up to two years postoperatively. The primary objective of this trial is to assess the feasibility of conducting of a multi-site randomized controlled trial to test the effect of a comprehensive prehabilitation program versus standard care for men with prostate cancer undergoing radical prostatectomy. We hypothesize that men with prostate cancer undergoing radical prostatectomy in the comprehensive prehabilitation program (full-body exercises and pelvic floor muscle exercises) will report better health-related quality of life, urological symptoms, and physical fitness, physical activity, and pain, as well as a shorter postoperative length of stay than participants receiving standard preoperative care (pelvic floor muscle exercises alone). Our secondary objective is to report estimates of efficacy on several clinically important outcomes for this population that will be used for sample size calculations in an adequately powered trial.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02036684
Study type Interventional
Source University of Guelph-Humber
Contact
Status Completed
Phase Phase 1/Phase 2
Start date November 2013
Completion date May 17, 2016

See also
  Status Clinical Trial Phase
Completed NCT02233608 - Advanced Pelvic Floor Training Program for Prostate Cancer Surgery Phase 1/Phase 2