International Cancer of the Head and Neck, Genetics and Environment (InterCHANGE) Study

Assess the Effect of Genetic Factors, Including Both SNP and Copy Number Variation (CNV) Through Analysis of Both Main Effect and Gene-gene Interaction Clinical Trial

— InterCHANGE  

Official title:

International Cancer of the Head and Neck, Genetics and Environment (InterCHANGE) Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01972802
• Other study ID #: 201006077R
• Status: Recruiting
• Phase: N/A
• First received: October 24, 2013
• Last updated: October 29, 2013
• Start date: January 2011
• Est. completion date: December 2014

Study information

• Verified date: October 2013
• Source: National Taiwan University Hospital
• Contact: Pei-Jen Lou
• Phone: +886-23123456
• Email: pjlou[@]ntu.edu.tw
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Observational

Clinical Trial Summary

Our overall objective is to understand the role of lifestyle factors, genetics and HPV infection in the development and prognosis of head and neck cancer particularly in Asia.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 900
• Est. completion date: December 2014
• Est. primary completion date: December 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

Age 18~80 Incident head and neck cancer patients

• Oral, oropharynx and hypopharynx (C00-C14)

• Laryngreal cancer (C32)

• *Esophageal cancer if possible (C15)

Exclusion Criteria:

• Salivary gland (C07-C08)

• Nasopharynx (C11)

• Thyroid (C79.3)

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Alcohol Drinking
• Assess the Effect of Genetic Factors, Including Both SNP and Copy Number Variation (CNV) Through Analysis of Both Main Effect and Gene-gene Interaction
• Evaluate the Association Between Certain Environmental Exposures (e.g. Cigarette Smoking, Alcohol Drinking, Betel Nut Chewing…) and Head and Neck Cancers
• Head and Neck Neoplasms

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Tiapei	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	head and neck cancer risk factor	evaluate the association between certain environmental exposures (e.g. cigarette smoking, alcohol drinking, betel nut chewing…) and head and neck cancers,assess the effect of genetic factors, including both SNP and copy number variation (CNV) through analysis of both main effect and gene-gene interaction	Four years	Yes