Nasopharyngeal Carriage of Streptococcus Pneumoniae Clinical Trial
Official title:
Effects of Pneumococcal Vaccine on Nasopharyngeal Carriage: a FinIP Effectiveness Trial Satellite Study During PCV National Vaccination Programme
The purpose of this study is to assess the direct effects of the ten-valent pneumococcal
conjugate vaccine administered to infants on nasopharyngeal carriage at 3 to 5 years of age.
These children have been vaccinated in infancy in the cluster-randomized Finnish Invasive
pneumococcal Disease (FinIP) Trial (a separate protocol reported at ClinicalTrials.gov
Identifier:NCT00861380) during 2009 to 2011.
Also the indirect effect on nasopharyngeal carriage will be assessed on vaccinees' elder
non-vaccinated siblings aged 5 to 9 years.
This study includes a cross-sectional sampling of nasopharyngeal and oropharyngeal swabs in 2013 from vaccinated and unvaccinated children. ;