Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures

Identify the Presence of a Marker of Ischemia/Hypoperfusion of the Brain Via Peripheral Blood Clinical Trial

Official title:

Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01639534
• Other study ID #: HM12941
• Status: Completed
• Start date: March 2011
• Est. completion date: October 9, 2013

Study information

• Verified date: July 2018
• Source: Virginia Commonwealth University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of the study is to determine if a new blood test can help the doctor determine if there is brain injury or ischemia. Ischemia occurs when not enough oxygen gets to the brain. In this study the investigators are analyzing your blood for a new test that might help doctors decide if symptoms are from a neurologic problem.

Description:

We will compare a new blood test with routine tests that the doctor will order as part of your normal care. This study will measure new biomarkers (biomarker is a specific distinguishing feature used to measure or indicate the effects or progress of a disease or condition) of neurologic stress called xanthine, hypoxanthine, and inosine. Blood will be drawn as a part of the study to measure these biomarker levels in your blood. This blood will be analyzed i the laboratory at Virginia Commonwealth University and possibly at a future date at another institution. No names will be associated with the blood sample

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: October 9, 2013
• Est. primary completion date: October 9, 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Men and Women over age of 18 non

• Women who are not pregnant

• Subject who are not prisoners

• Subjects presenting to the operation room for a Carotid artery stenting procedure

• Hemoglobin greater than or equal to 11mg/dl

• Subjects who speak english

• Subjects 18 years of age or older

Exclusion Criteria:

• Hemoglobin less than 11mg/dl

• Women who are pregnant

• Children under age of 18

• Prisoners

• Non English

Related Conditions & MeSH terms

• Identify the Presence of a Marker of Ischemia/Hypoperfusion of the Brain Via Peripheral Blood
• Ischemia
• Ischemia/Hypoperfusion of Brain

Locations

Country	Name	City	State
United States	Virginia Commonwealth University	Richmond	Virginia

Sponsors (1)

Lead Sponsor	Collaborator
Virginia Commonwealth University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Biomarkers of Ischemia: Levels of Xanthine, Hypoxanthine and Inosine during Carotid Stenting Procedures	To compare a new blood test with can help the doctor determine if there is a brain injury or ischemia, The study will measure new biomarkers of neurologic stress called xanthine, hypoxanthine and inosine. Blood will be drawn as a part of the study to measure these biomarker levels in the blood. The blood will be analyzed in the laboratory at VCU.	analysis will occur after all samples collected