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Clinical Trial Summary

The goal of the present study is to investigate the clinical outcomes of patients with gastrointestinal bleeding originating from the small intestine following diagnostic investigation with single balloon enteroscopy. We hypothesize that single balloon enteroscopy can arrive at a diagnosis and provide therapeutics in a majority of patients with gastrointestinal bleeding originating in the small intestine.


Clinical Trial Description

The small intestine has been, until recent years, a black box to gastroenterologists because it is difficult to see and reach. Radiological imaging provides little details of small intestinal mucosa. Capsule endoscopy, introduced in 2001, enables gastroenterologists to visualize the entire small intestine from within for the first time, but it is only a diagnostic tool. Single-balloon enteroscopy (SBE) is a new enteroscopy methods that use an overtube with one balloon or a spiral to help pleat bowel onto the endoscope and allow examination of the distal small bowel. This methods allow for biopsy, hemostasis, and other therapeutic interventions to be performed in the small bowel. Early reports have been promising; with 50-70% diagnostic yield for small bowel pathology reported in the literature. However, despite these promising results the impact SBE findings on patient outcomes is not clear. ;


Study Design

Observational Model: Cohort


Related Conditions & MeSH terms


NCT number NCT01625585
Study type Observational
Source Washington University School of Medicine
Contact
Status Completed
Phase N/A
Start date May 2011

See also
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Completed NCT00964496 - Long-term Effects of Thalidomide for Recurrent Gastrointestinal Bleeding Due to Vascular Malformation Phase 2
Completed NCT00203619 - Capsule Endoscopy in Obscure GI Bleeding N/A
Active, not recruiting NCT05731388 - Assessing Depth of Small Bowel Insertion at Push Enteroscopy by Using Capsule Endoscopy
Terminated NCT02315404 - Cap Assisted Balloon Enteroscopy Versus Conventional Balloon Enteroscopy In The Evaluation Of Obscure Gastrointestinal Bleeding: A Randomized Controlled Trial N/A
Recruiting NCT04646083 - Depth of Maximal Ileal Insertion During Retrograde Enteroscopy With TTS Balloon
Completed NCT04821349 - Role of AI in CE for the Identification of SB Lesions in Patients With Small Intestinal Bleeding. N/A
Recruiting NCT05140057 - Preparation Regimens to Improve Capsule Endoscopy Visualization and Diagnostic Yield N/A