Lambert-Eaton Myasthenic Syndrome Clinical Trial
Official title:
Inpatient Double-Blind Placebo-Controlled Withdrawal Study of 3,4-Diaminopyridine Base (3,4-DAP) in Subjects With Known Lambert-Eaton Myasthenic Syndrome
Hypothesis: 3,4-Diaminopyridine base (3,4-DAP) improves Lambert-Eaton Myasthenic Syndrome (LEMS)-related weakness.
The objectives of the study were to confirm the safety and to test the efficacy of 3,4-DAP in
the treatment of LEMS-related weakness.
This was a phase 2 randomized double-blind placebo-controlled withdrawal study in subjects
with known clinically active LEMS who had been on a chronic stable dose of compassionate
distribution Jacobus 3,4-DAP provided through FDA-approved individual investigator-held INDs.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| No longer available |
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| Approved for marketing |
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