Systemic Inflammatory Response Syndrome Clinical Trial
Official title:
The Relation Between Systemic Inflammatory Markers and Acute Pain in TKA
In this study we evaluate if there is a correlation between acute pain and systemic inflammatory markers after total Knee Arthroplasty (TKA).
Status | Completed |
Enrollment | 120 |
Est. completion date | October 2011 |
Est. primary completion date | October 2011 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Elective unilateral primary total knee arthroplasty - Able to speak and understand danish - Able to give informed consent Exclusion Criteria: - Alcohol or medical abuse - Allergies to local anesthetics or methylprednisolone - Age < 18 years old - Daily use of strong opioids or glucocorticoids - Pregnancy or breastfeeding (fertile women) - Bilateral / revision arthroplasty - Dementia or other cognitive dysfunction - Diabetic neuropathy, rheumatoid arthritis, and neurologic or psychiatric diseases potentially influencing pain perception |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Denmark | Dep. of Anesthsiology, Hvidovre University Hospital | Copenhagen | Hvidovre |
Lead Sponsor | Collaborator |
---|---|
Hvidovre University Hospital |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Systemic inflammation vs. pain | The correlation between pain and systemic inflammatory markers (CRP and IL6) | 1 week | No |
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