Primary Non-operated Squamous Cell Carcinoma of Hypopharynx Clinical Trial
Official title:
Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck: a Multicenter, Two-arm, Randomized Phase II Trial.
Severe acute and late dysphagia is now considered as a dose-limiting toxicity of
radio(chemo)therapy for head and neck cancer that significantly affects patients' quality of
life. We propose to preserve swallowing function by:
- adapting (individualizing) treatment (intensity-modulated radiotherapy: IMRT) to
per-treatment changes occurring in the tumor and surrounding organs and tissues;
- reducing the volumes of elective neck, that may result in significant decrease of
severe acute and late dysphagia.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01341535 -
Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer.
|
Phase 2 |