Persistent Pulmonary Artery Hypertension After Valve Replacement — SALT  

Persistent Severe PH After Valve Therapy Clinical Trial

Official title: Persistence of Severe Pulmonary Artery Hypertension in Patients After vaLve replacemenT

Status Not yet recruiting

Clinical Trial Summary

Background: Persistent severe pulmonary hypertension (PH) after mechanical valve replacement is a frequent finding in patients with severe valve-diseases. The reasons to develop PH are multifactorial and the prevalence of severe PH significantly worsens the patients´ outcome.

Aims: (i) To define the prevalence of PH in patients after valve replacement and (ii) to identify factors predicting persistent PH.

Methods: All patients which underwent valve replacement at our institution between the years 2008 -2010 will be screened retrospectively. Those patients with pre- procedural proven PH by means of right-heart catheterization will receive prospective follow-up with echocardiography. Diagnosis of persistent PH will be confirmed with right heart catheterization.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Hypertension
• Hypertension, Pulmonary
• Persistent Severe PH After Valve Therapy

• NCT number: NCT01238731
• Study type: Observational
• Source: University Hospital, Bonn
• Contact: Christoph Hammerstingl, MD
• Phone: +4922815951
• Email: christoph.hammerstingl@ukb.uni-bonn.de
• Status: Not yet recruiting
• Phase: N/A
• Start date: January 2011
• Completion date: March 2012