Nasopharyngeal Carriage of S. Pneumoniae Clinical Trial
Official title:
Streptococcus Pneumonia: Herd Effects and Emergence of Potentially Virulent Serotypes PCV13_Impact of NP Colonization, Herd Effects and Emergence of Potentially Virulent Serotypes of Pneumococci
The specific aim is to evaluate the impact of PCV13 as administered in the pediatric primary
care clinic at Boston medical center on the serotype specific carriage of Streptococcus
pneumoniae in children < 5 and their parents.
Specifically the investigators will measure the decline in vaccine serotypes, the proportion
of children receiving vaccine required to achieve 50% reduction in serotype specific
carriage and the correlation between immunogenicity of the specific serotypes and decline in
carriage.
n/a
Time Perspective: Prospective