Adult Acute Myeloid Leukemia in Remission Clinical Trial
Official title:
Genetic Predictors of AML Treatment Response
Verified date | May 2016 |
Source | Children's Oncology Group |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Observational |
This research trial studies deoxyribonucleic acid (DNA) in blood or bone marrow samples from younger patients with acute myeloid leukemia. Studying samples of blood and bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how well patients will respond to treatment.
Status | Completed |
Enrollment | 2500 |
Est. completion date | |
Est. primary completion date | May 2016 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A to 30 Years |
Eligibility |
Inclusion Criteria: - Diagnosis of AML - In remission - Adequate DNA from peripheral blood or bone marrow samples - Concurrent enrollment on CCG-2961, COG-AAML03P1, COG-AAML0531, AML-93, AML-97, AML-04,AML-09, or Canada AML Infection clinical trial required |
Observational Model: Cohort, Time Perspective: Cross-Sectional
Country | Name | City | State |
---|---|---|---|
United States | Children's Oncology Group | Philadelphia | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
Children's Oncology Group | National Cancer Institute (NCI) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Incidence of first acute myeloid leukemia relapse | Up to 2 years | No | |
Primary | Rate of invasive bacterial infections defined as the number of invasive infection episodes divided by the days at risk | From study entry date to completion of therapy date provided on the final Reporting Period case reporting form, assessed up to 2 years | No |
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