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Clinical Trial Summary

This randomized clinical trial is evaluating the impact of a positive psychology intervention (PATH) on anxiety symptoms, depression symptoms, and quality of life in survivors of hematopoietic stem cell transplant (HSCT) compared to usual care.


Clinical Trial Description

Patients undergoing hematopoietic stem cell transplantation (HSCT) deal with numerous physical and psychological symptoms during acute hospitalization and recovery. Of the few psychosocial interventions tailored to the needs of the HSCT population, most focus on the needs of patients in the pre-transplant phase or during the HSCT hospitalization, but not during the acute recovery period starting at 100-days post-HSCT. Hence, the investigators developed a remotely-delivered positive psychology intervention, Positive Affect in the Transplantation of Hematopoietic Stem Cells (PATH). This intervention encourages patients to perform simple and enjoyable structured activities that increase the intensity of positive thoughts and emotions. With this multi-site randomized clinical trial, the investigators aim to find out whether PATH can improve psychological distress and quality of life in HSCT survivors, compared to usual care, using validated assessment tools. ;


Study Design


Related Conditions & MeSH terms

  • Hematopoietic Stem Cell Transplant

NCT number NCT06328127
Study type Interventional
Source Brigham and Women's Hospital
Contact Hermioni Amonoo, MD, MPP
Phone 617-732-5056
Email hermioni_amonoo@dfci.harvard.edu
Status Not yet recruiting
Phase N/A
Start date June 1, 2024
Completion date April 30, 2029

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