Clinical Trials Logo
  1. Home
  2. Other
  3. NCT06058494

Multi-scale Modeling for Predictive Characterization of Ligaments and Grafts Behavior in ACL Reconstruction — MULTI-ACL  

Anterior Cruciate Ligament Reconstruction Clinical Trial

Official title:
Multi-scale Modeling for Predictive Characterization of Ligaments and Grafts Behavior in ACL Reconstruction

Clinical Trial Summary

The objective of this clinical trial is provide in vivo data thus to model the ligament biomechanical behavior within the physiologically healthy joint and to use the implemented model to predict risk and success rates focusing on knee joint Anterior Cruciate Ligament (ACL) reconstruction. Current ACL surgery offers 3 alternatives: autografts, allografts and bioengineered grafts; the choice of the implant and its characteristics still remains a critical point. The knowledge of patient-specific joint and graft biomechanics is fundamental to reduce surgical revision rate and low functional outcome. This clinical trial will provide data coming from patient-specific biomechanics into a prognostic computational model, able to provide information on both the optimal customized reconstruction and graft status during the early rehabilitation phase. This patient-specific approach will lead to quicker return to sports activity, reducing also the possibility of early osteoarthritis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Anterior Cruciate Ligament Reconstruction
Clinical Trial Details
NCT number NCT06058494
Study type Observational
Source Istituto Ortopedico Rizzoli
Contact
Status Completed
Phase
Start date November 1, 2015
Completion date March 1, 2021
View Details
See also
  Status Clinical Trial Phase
Completed NCT06280456 - Tranexamic Acid Injection With Different Drainage Clamping Time After Anterior Cruciate Ligament Reconstruction N/A
Active, not recruiting NCT02772770 - Pediatric ACL: Understanding Treatment Options
Terminated NCT00300300 - Anterior Cruciate Ligament (ACL) Reconstruction Using Different Grafts and Surgical Techniques Phase 4
Completed NCT00775892 - SeriACL™ Device (Gen IB) Trial for Anterior Cruciate Ligament (ACL) Repair Phase 1/Phase 2
Completed NCT04504344 - Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction Phase 1
Recruiting NCT06327555 - Study on the Effect of Telerehabilitation Using Wearable Devices After ACL Reconstruction N/A
Recruiting NCT05968729 - Assessment of Gait Adaptation Due to an Asymmetric Walking Protocol N/A
Not yet recruiting NCT05972876 - Graft Maturity After Blood Flow Restriction Training in ACL Reconstruction N/A
Withdrawn NCT03688477 - Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation N/A
Completed NCT02945553 - Prevention of Skeletal Muscle Adaptations to Traumatic Knee Injury and Surgery Phase 1/Phase 2
Recruiting NCT01279759 - Follow up of Patients Operated With Anterior Cruciate Ligament Reconstruction N/A
Completed NCT00245271 - Safety of OMS103HP in Patients Undergoing Anterior Cruciate Ligament (ACL) Reconstruction Phase 3
Recruiting NCT06131047 - High Intensity Resistance Training With and Without Blood Flow Restriction in ACL Reconstruction N/A
Recruiting NCT06430775 - Exploring Prolonged AMR in ACL Reconstructed Patients
Recruiting NCT06206200 - The Effect of Cognitive Dual-task Rehabilitation on Arthrogenic Muscle Responses After ACL Reconstruction N/A
Not yet recruiting NCT06318039 - Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction N/A
Recruiting NCT03336060 - Neurophysiologic Correlates of Movement Planning During Complex Jump Landing Tasks and the Role of Cognitive Function N/A
Completed NCT03304561 - The Effect of Contralateral Limb Training on Functional Outcomes in Patients With ACL Reconstruction N/A
Not yet recruiting NCT05619393 - Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People N/A
Completed NCT02604550 - Anterior Cruciate Ligament Pain Study Phase 4