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Decremental Esophageal Catheter Filling Volume Titration For Transpulmonary Pressure Measurement — DECFVTTPM  

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
Decremental Esophageal Catheter Filling Volume Titration For Esophageal Pressure Measurement

Clinical Trial Summary

Mechanical ventilation is a critical intervention in the management of pediatric patients with respiratory distress. During this process, accurate measurement of transpulmonary pressure (PL) is essential to ensure the safety and efficacy of ventilation. PL is defined as the difference between alveolar pressure (Palv) and pleural pressure (Ppl). While the direct measurement of Ppl is possible, it poses a risk to tissue integrity. Thus, the primary surrogate for Ppl measurement today is esophageal pressure (Pes). However, the measurement of Pes is not without challenges. This abstract outlines the pitfalls associated with Pes measurement, emphasizing the importance of employing well-defined procedures to mitigate potential errors. These errors can range from underestimation of Pes due to underfilled catheters to overestimation resulting from overfilled catheters. To address these challenges and optimize Pes measurement, various methods have been proposed for titrating the filling volume of the esophageal catheter. In this study, investigators aim to assess a faster decremental filling method and compare it to the traditionally accepted Mojoli method in the context of pediatric patients. This research seeks to enhance the intensivists' understanding of the most efficient and accurate approach to Pes measurement during mechanical ventilation in the pediatric population, ultimately contributing to improved patient care and outcomes

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06051292
Study type Interventional
Source Dr. Behcet Uz Children's Hospital
Contact Hasan Agin, Professor
Phone 05362013162
Email hasanagin@gmail.com
Status Recruiting
Phase N/A
Start date September 18, 2023
Completion date December 30, 2024
View Details
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