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Clinical Trial Summary

the presence of cesarean section niche has adverse effects on success of ART outcome


Clinical Trial Description

A common finding by ultrasound in secondary infertility patients with previous cesarean sections is the presence of niche, which is formally defined as an indentation of the uterine myometrium of at least 2 mm at the site of the caesarean scar. The most common symptom of niche is abnormal uterine bleeding, other symptoms include dysmenorrhea, chronic pelvic pain, dyspareunia, and sub-fertility/infertility. It has been reported that a niche can reduce the chances of embryo implantation and may lead to spontaneous miscarriages if the implantation is close to or in the niche. The presence of a niche may render the actual embryo transfer procedure technically more difficult, and clinicians need to be aware of its presence and perform the transfer under ultrasound guidance to ensure the catheter bypasses the niche and enters the uterine cavity. Still the impact of c.s niche and its characteristics on outcome of ART is not clear. ;


Study Design


NCT number NCT05966558
Study type Observational
Source Zagazig University
Contact eman elgingy, M.D
Phone +20 122 749 1143
Email eman_elgindy2013@hotmail.com
Status Recruiting
Phase
Start date January 22, 2020
Completion date October 1, 2024