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Clinical Implication of Aflibercept in PCV Treatment in China

Polypoidal Choroidal Vasculopathy Clinical Trial

Official title:
Aflibercept Observational Study for the Clinical Use of PCV in China, Polycentric, Observational, Retrospective-prospective Study

Clinical Trial Summary

The purpose of this study is to evaluate the overall treatment characteristics and efficacy of Aflibercept in the treatment of PCV in China through a multicenter, observational, prospective-retrospective study. This study is a long-term follow-up cohort, plans to unite a total of 30 hospitals in different regions of the China to enroll 1000 PCV patients. Main evaluation indicators: To observe the changes in visual acuity (BCVA) in PCV patients treated with Aflibercept to evaluate the effectiveness of the treatment.

Clinical Trial Description

Primary Study Objective(s) To provide overall treatment characteristics of aflibercept in PCV treatment Secondary Study Objective(s) 1. To describe the treatment regimens of aflibercept treatment on PCV in clinical practice. 2. To evaluate effectiveness of aflibercept treatment on PCV including vision gain (BCVA) and anatomic improvement (CRT, Polyps regression, Polyps inactivity, and PED) 3. To explore the relative factors of aflibercept treatment effectiveness. 4. To describe patients' tolerance to anti-VEGF and PDT treatment. 5. To collect safety information with aflibercept treatment in a wider population setting ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05639660
Study type Observational [Patient Registry]
Source Peking Union Medical College Hospital
Contact Youxin Chen, Professor
Phone +86 13801025972
Email chenyx@pumch.cn
Status Recruiting
Phase
Start date January 1, 2021
Completion date November 30, 2024
View Details
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