Acne Scars - Mixed Atrophic and Hypertrophic Clinical Trial
Official title:
Microneedling With Topical Glycolic Acid 35% Versus Microneedling With Topical Insulin in the Treatment of Atrophic Post-acne Scars
Verified date | February 2023 |
Source | Zagazig University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
To examine the anti-scarring effect of topical glycolic acid 35% combined with microneedling against that of topical insulin combined with microneedling for post acne scars
Status | Not yet recruiting |
Enrollment | 30 |
Est. completion date | December 1, 2023 |
Est. primary completion date | September 1, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - All types of facial atrophic acne scars - Patients aged >18 years - Both sexes Exclusion Criteria: - Pregnancy and lactation - Active acne or any active facial lesion - History of keloid scar - History of systemic diseases as DM or hypotension - Bleeding and coagulation disorders - Infection and immunosuppression |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Zagazig University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Goodman and Baron's acne scar grading system | Grade 1 Erythematous hypo or hyperpigmented flat marks Grade 2 Mild atrophy not obvious at social distance of >/=50 cm or easily covered by makeup or beard hair in male Grade 3 Moderate atrophy obvious at social distance of >/=50 cm, not easily covered by makeup or beard hair but able to be flattened by manual stretching of the skin Grade 4 Sever atrophy obvious at social distance >50 cm, not easily covered by makeup and not able to be flattened by manual stretching of skin | through study completion, an average of 1 year | |
Primary | Quartile grading system | The improvement of patients is evaluated as follow:
Poor (improvement < 25%) Mild (improvement 26%-50%) Good (improvement 51%-75%) Excellent (improvement >75%) |
through study completion, an average of 1 year | |
Primary | 5 point scale for evaluating patient's satisfaction | None (no satisfaction) Mild (1%-25% satisfaction) Moderate (26%-50% satisfaction) Good (51%-75% satisfaction) Very good (76%-100% satisfaction) | through study completion, an average of 1 year | |
Primary | Pain assessment | Pain during the session will be assessed and graded as mild, moderat and sever (Saadawi et al., 2018). | through study completion, an average of 1 year |
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