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QA102 Phase II Study in Subjects With Dry AMD — AMEND  

Dry Age-related Macular Degeneration Clinical Trial

Official title:
A Phase 2, Double-Masked, Randomized, Placebo-Controlled, Dose-Response Study Assessing the Safety and Efficacy of QA102 in Subjects With Dry Age-Related Macular Degeneration (AMD)

Clinical Trial Summary

This is a phase 2, double-masked, randomized, placebo-controlled, dose-response study. The primary objective of the study is to evaluate the efficacy of QA102 oral capsules on the development of soft drusen, visual acuity (VA), and geographic atrophy (GA) or choroidal neovascularization (CNV) or the progression of GA in subjects with intermediate to advanced dry AMD.

Clinical Trial Description

Approximately 30 sites will randomize a total of approximately 150 subjects to 1 of 3 treatment arms in a 1:1:1 ratio (50 subjects per arm). Each subject will receive either QA102 or matching placebo BID for up to 15 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05536752
Study type Interventional
Source Smilebiotek Zhuhai Limited
Contact
Status Active, not recruiting
Phase Phase 2
Start date September 22, 2022
Completion date January 2025
View Details
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