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Clinical Trial Summary

A Prospective, Randomized, Open-Label, Multicenter Clinical Trial study to compare the efficacy and safety of ATRA plus eltrombopag compared to eltrombopag monotherapy in the treatment of steroid-resistant/relapsed immune thrombocytopenia (ITP).


Clinical Trial Description

The investigators are undertaking a parallel group, multicenter, randomized controlled trial of patients with ITP in China. Patients were tested for MSCs, and they were divided into MSC-C5b-9+ group and MSC-C5b-9- group according to the test results, and the two groups were randomized to ATRA + eltrombopag and eltrombopag monotherapy group. Platelet count, bleeding and other symptoms were evaluated before and after treatment. Adverse events are also recorded throughout the study. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05438875
Study type Interventional
Source Peking University People's Hospital
Contact Xiaohui Zhang, MD
Phone +8613522338836
Email zhangxh100@sina.com
Status Recruiting
Phase Phase 3
Start date October 12, 2022
Completion date March 31, 2025

See also
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