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Camrelizumab Combined With Apatinib Versus Apatinib Alone in the Third-line Treatment of Metastatic Gastric Cancer

Metastatic Gastroesophageal Junction Adenocarcinoma Clinical Trial

Official title:
Prospective, Randomized, Single-center Phase II Clinical Study of Camrelizumab Combined With Apatinib Versus Apaitnib Alone in the Third-line Treatment of Metastatic Gastric Cancer

Clinical Trial Summary

This is a study of Camrelizumab combined with Apatinib versus Apatinib alone in the third-line treatment of metastatic gastric cancer. Paticipants will be radomized to receive treatment of Camrelizumab combined with Apatinib or Apatinib alone. The primary study hypothesis is that the adding Camrelizumab to Apatinib can prolong the progressive-free survival of the paticipants.

Clinical Trial Description

Camrelizumab 200mg intravenously 30 - 60 min biweekly; Apatinib mesylate 250mg or 500mg oral daily continuously; The treatment lasts for up to 2 years or until disease progression, death or intolerable toxicity occurred. ;

Study Design

Related Conditions & MeSH terms

  • Adenocarcinoma
  • Metastatic Gastric Adenocarcinoma
  • Metastatic Gastroesophageal Junction Adenocarcinoma
Clinical Trial Details
NCT number NCT05342389
Study type Interventional
Source Sixth Affiliated Hospital, Sun Yat-sen University
Contact Jian Xiao, PhD
Phone 13711114566
Email xiaoj26@mail.sysu.edu.cn
Status Not yet recruiting
Phase Phase 2
Start date May 1, 2022
Completion date November 1, 2023
View Details
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