Clinical Trials Logo
  1. Home
  2. Other
  3. NCT05341999

Effect of Cryotherapy Versus Post-operative Ibuprofen Medication on Post-operative Pain in Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis

Symptomatic Irreversible Pulpitis Clinical Trial

Official title:
Evaluation of the Effect of Cryotherapy Versus Post-operative Ibuprofen Medication on Post-operative Pain in Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis: a Randomized Controlled Trial

Clinical Trial Summary

Evaluation of the effect of cryotherapy versus post-operative ibuprofen medication on post-operative pain in mandibular molar teeth with symptomatic irreversible pulpitis . a new technique was proposed to utilize the effect of cold saline on reducing the inflammatory process in the tissue, the so-called cryotherapy.

Clinical Trial Description

PICO/ Population: Molar teeth with symptomatic irreversible pulpitis. Intervention I: Final irrigation with cold saline (cryotherapy). Intervention II: Ibuprofen post-operative medication. Control: Final irrigation with normal saline, and no post-operative medication. Outcome: Post- operative pain. Sequence of Procedural steps: 1. Full medical and dental history will be obtained from all the patients . 2. Thorough clinical and radiographic examination for the tooth to be treated will be done. 3. The tooth will be anaesthetized and Access cavity will be performed. 4. The canals will be thoroughly irrigated using 3ml syringe of Sodium hypochlorite after every instrument. 5. Canals will be dried using sterile paper points. 6. In the intervention group 1, cryotherapy irrigation will be done using 20ml of 2.5°C cold saline for 5 min, the cold saline will be stored in an icebox with a thermometer calibrated at 2.5°C. 7. In the intervention group 2, the patients will be prescribed ibuprofen medication as a single dose immediately after completion of root canal treatment. 8. In the control group, final irrigation will be done using normal saline at room temperature. 9. Canals will be dried using sterile paper points, and then filled with gutta percha cones corresponding to the same size of the final shaping file and sealed with sealer. 10. The access cavity will then be closed with temporary filling. 11. Post-operative instructions will be given to all patients. • The patient will be asked to rate their pain level according to the given instructions and telecommunication will be scheduled after 3 days to collect the VAS scores and assess the outcome of the treatment. The patients who will be suffered from severe pain, analgesic will be prescribed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05341999
Study type Interventional
Source Cairo University
Contact Yousef H Abuhelal, Master
Phone +201033054851
Email yousefhassan@dentistry.cu.edu.eg
Status Not yet recruiting
Phase Phase 1
Start date April 2022
Completion date May 2023
View Details
See also
  Status Clinical Trial Phase
Completed NCT04552132 - Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator N/A
Recruiting NCT05338671 - Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment Phase 4
Completed NCT04186897 - Occlusal Reduction Effect on Postendodontic Pain N/A
Recruiting NCT03725579 - Anesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine Phase 2/Phase 3
Completed NCT03692039 - Comparison Between M-Pro and ProTaper Next N/A
Not yet recruiting NCT03716635 - Effect of Cryotherapy on Postoperative Pain N/A
Completed NCT05199181 - Full Pulpotomy in Mature Teeth With Symptomatic Irreversible Pulpitis as a Routine Treatment in the Primary Care Clinics N/A
Completed NCT03553641 - The Effect of Central Sensitization on Assessment Capacity of Patients
Not yet recruiting NCT03890835 - Pulpotomy in Mature Permanent Molars Using Biodentine Versus MTA N/A
Completed NCT03335007 - Pretreatment Aceclofenac Effect on Pain and Analgesic Intake After Endodontic Treatment Phase 2/Phase 3
Not yet recruiting NCT05238727 - Volume Increase Versus Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Block Success N/A
Not yet recruiting NCT04608981 - Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression Phase 4
Not yet recruiting NCT06298383 - The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain N/A
Completed NCT05982392 - Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain Phase 2/Phase 3
Completed NCT05306470 - Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa N/A
Completed NCT05488925 - Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block. Phase 4
Completed NCT04961268 - Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis N/A
Completed NCT04119661 - Postendodontic Pain on Using Max-i-Probe vs NaviTip as Irrigation Needles N/A
Completed NCT04202406 - Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpitis N/A
Not yet recruiting NCT04593160 - Efficacy of Preoperative Diclofenac Potassium- Acetaminophen Combination on Anesthetic Success in Patients With Symptomatic Irreversible Pulpitis: a Randomized Controlled Trial N/A