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Clinical Trial Summary

This is a Phase 1/2 study to evaluate the safety, clinical activity, pharmacokinetics (PK), and pharmacodynamics (PD) of ZN-c3 in combination with niraparib in subjects with platinum-resistant ovarian cancer.


Clinical Trial Description

This is a Phase 1/2 open-label, multicenter study to evaluate the safety, clinical activity, PK, and PD of ZN-c3 in combination with niraparib in subjects with platinum-resistant ovarian cancer who have failed Poly (ADP-ribose) polymerase inhibitor (PARPi) maintenance treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05198804
Study type Interventional
Source K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Contact Project Director
Phone (858) 263-4333
Email medicalaffairs@zentalis.com
Status Recruiting
Phase Phase 1/Phase 2
Start date January 27, 2022
Completion date November 2023

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