Postoperative Nausea and Vomiting Clinical Trial
Official title:
Dexmedetomidine for Prophylaxis Against Postoperative Nausea and Vomiting in Highly Susceptible Patients: a Randomised Controlled Comparison of Two Bolus Doses
The study aims to compare between two bolus doses of dexmedetomidine in preventing PONV in highly susceptible patients.
Being A challenging complaint, many studies tried to find an effective preventive strategies for PONV. In this study protocol the investigators aim to compare between 0.5 mic/kg and 0.75 mic/kg bolus doses of dexmedetomidine when given toward the end of head and neck surgeries in highly susceptible patients with a controlled group receiving ondansetron. The primary outcome is the 1st 24 hours incidence of PONV Other outcomes include: - Time to 1st call for rescue antiemetic and the total amount of antiemetics - Number of PONV attacks - Post operative pain score with visual analogous scale (VAS) and time to 1st call for rescue analgesia - Sedation Score using Observer's Assessment of Alertness and sedation (OAA/S) - Patient satisfaction - Vital signs in the 1st 24 hours ;
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