The Efficacy and Safety of Switching to Flumatinib Versus Dasatinib After Imatinib-related Low-grade Adverse Events in CML-CP Patients

Chronic Myeloid Leukemia in Chronic Phase Clinical Trial

Official title: The Efficacy and Safety of Switching to Flumatinib Versus Dasatinib After Imatinib-related Low-grade Adverse Events in Patients With Chronic Myeloid Leukemia in Chronic Phase: an Randomized Controlled Trial.

Status Recruiting

Clinical Trial Summary

The purpose of this study is to explore the efficacy and safety of switching to flumatinib versus dasatinib after imatinib-related low-grade adverse events in patients with chronic myeloid leukemia in chronic phase (CML-CP) in China. This is a post-marketing, interventional, double-arm, prospective, open-label, randomized controlled study in CML-CP patients in China. Patients will be recruited consecutively from the study sites during the enrollment period. The enrolled patients will be given flumatinib or dasatinib under the conditions of informed consent and frequent monitoring according to the clinical guideline.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Chronic Myeloid Leukemia in Chronic Phase
• Leukemia
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive
• Leukemia, Myeloid

• NCT number: NCT04933526
• Study type: Interventional
• Source: Shenzhen Second People's Hospital
• Contact: Xin Du
• Phone: 075583366388
• Email: duxingz@medmail.com.cn
• Status: Recruiting
• Phase: Phase 4
• Start date: July 1, 2021
• Completion date: June 30, 2023