Other Clinical Trial - Antithrombin III & Post-liver Transplantation Acute

Clinical Trial Summary

The reno-protective effect of Antithrombin III (ATIII) has been well-studied in various animal studies; however, little is known about the effect of ATIII on kidney function in patients undergoing liver transplantation (LT). This study aimed to determine the association between preoperative ATIII level and postoperative acute kidney injury (AKI) after LT (post-LT AKI).

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Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

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Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
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NCT number	NCT04912193
Study type	Observational [Patient Registry]
Source	Asan Medical Center
Contact
Status	Completed
Phase
Start date	January 4, 2010
Completion date	December 31, 2019

Antithrombin III and Post-liver Transplantation Acute Kidney Injury

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms