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Clinical Trial Summary

This is a dose-escalation, single-arm, single-center open study which aims to evaluate the maximum tolerated dose (MTD) and dose-dependent toxicity (DLT) of a novel oncolytic vaccinia virus expressing bispecific antibody RGV004 in patients with relapsed/refractory B-cell lymphoma,


Clinical Trial Description

Oncolytic vaccinia virus administered by intratumoral injection ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04887025
Study type Interventional
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Wenbin Qian
Phone +8613605801032
Email qianwb@zju.edu.cn
Status Recruiting
Phase Phase 1
Start date February 8, 2022
Completion date March 15, 2025

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