Clinical Trials Logo
  1. Home
  2. Other
  3. NCT04775420
  4. Details
NCT04775420 Clinical Trial

MPV and NLR as Predictors of SBP Diagnosis

Spontaneous Bacterial Peritonitis Clinical Trial

Official title:
Mean Platelet Volume (MPV) and Neutrophil to Lymphocyte Ratio (NLR) as Predictors of Spontaneous Bacterial Peritonitis in Cirrhotic Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04775420
Other study ID # Soh-Med-21-02-22
Secondary ID
Status Completed
Phase
First received
Last updated
Start date April 1, 2020
Est. completion date April 30, 2022

Study information
Verified date January 2023
Source Sohag University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).

Recruitment information / eligibility
Status Completed
Enrollment 332
Est. completion date April 30, 2022
Est. primary completion date April 30, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Decompensated liver cirrhosis ascetic patients. Exclusion Criteria: - Immunocompromised patients. - Patients who had received antibiotics before hospital admission. - Patients on anticoagulant medications, NSAIDs, or oral contraceptive drugs. - Patients with heart failure, diabetes mellitus, hypertension, hyperlipidemia, peripheral vascular disease, hematological disorders, and neoplastic disorders and patients with clinically overt hypothyroidism or hyperthyroidism or with clinically and laboratory-evident autoimmune diseases.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)
MPV and NLR are easily accessible and inexpensive tests

Locations
Country Name City State
Egypt Sohag Faculty of Medicine Sohag

Sponsors (1)
Lead Sponsor Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary The utility of MPV as non-invasive predictor of SBP It will be measured from CBC 1 year
Primary The utility of NLR as non-invasive predictor of SBP It will be measured from CBC 1 year
See also
  Status Clinical Trial Phase
Not yet recruiting NCT06026267 - Efficacy of Conventional Dose Protocol vs Low Dose Protocol Albumin Use in Patients With Cirrhosis and High Risk Spontaneous Bacterial Peritonitis N/A
Withdrawn NCT02552862 - Study of the Effect of Adjunctive Vivomixx® in Patients With Cirrhosis and Spontaneous Bacterial Peritonitis (SBP) Phase 3
Completed NCT01193426 - Diagnostic of Spontaneous Bacterial Peritonitis
Completed NCT02528097 - A Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis N/A
Completed NCT00359853 - Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis Phase 4
Active, not recruiting NCT04159870 - Rifaximin Versus Norfloxacin in Spontaneous Bacterial Peritonitis Phase 3
Completed NCT04153604 - Doxycycline for the Prevention of Spontaneous Bacterial Peritonitis
Completed NCT06234046 - Rifaximin as a Prophylaxis of Spontaneous Bacterial Peritonitis in Comparison With Ciprofloxacin Phase 3
Recruiting NCT01598870 - Diagnosis of Spontaneous Bacterial Peritonitis N/A
Recruiting NCT00761098 - Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) Phase 4
Completed NCT05401721 - Serum Copeptin in Cirrhotic Patients With Spontaneous Bacterial Peritonitis
Completed NCT02468089 - To Compare the Efficacy of Carbepenem Versus Carbepenem Plus GM-CSF in Difficult To Treat Spontaneous Bacterial Peritonitis N/A
Not yet recruiting NCT04746937 - Nitazoxanide in Prevention of Secondary Spontaneous Peritonitis Phase 3
Recruiting NCT02759497 - Evaluation of Serum Amyloid A in Early Diagnosis of Spontaneous Bacterial Peritonitis N/A
Completed NCT02608658 - Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With Decompensated Cirrhosis With Ascites N/A
Completed NCT02388035 - Cefotaxime Resistance in Treatment of Spontaneous Bacterial Peritonitis N/A
Completed NCT03163745 - Asymptomatic Spontaneous Bacterial Peritonitis in Patients With Decompensated Liver Cirrhosis
Completed NCT04273373 - Low Dose Albumin Versus Standard Dose Albumin in High Risk Spontaneous Bacterial Peritonitis. N/A
Active, not recruiting NCT04395365 - Primary Antibiotic Prophylaxis Using Co-trimoxazole to Prevent Spontaneous Bacterial Peritonitis in Cirrhosis Phase 3
Terminated NCT00570960 - Clinical, Inflammatory, and Economic Impact of Dextran 70 in Treating Spontaneous Bacterial Peritonitis Phase 4