Nasal Irrigation to Reduce COVID-19 Morbidity

Covid19 Clinical Trial

Official title: Nasal Irrigation to Reduce COVID-19 Morbidity

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate if using nasal irrigation, also known as nasal lavage, for 14 days after a positive test in high risk patients can reduce the severity of symptoms associated with COVID-19. Nasal lavage consists of running salt water in one nostril and out the other to get rid of germs. Nasal irrigation was done with either Betadine or baking soda to determine if adding an antimicrobial or changing the pH of the mucous helped. Hospitalization and death were compared for combined nasal irrigation groups to the CDC dataset of patients aged 50+

Clinical Trial Description

The purpose of this study is to evaluate if using nasal irrigation, also known as nasal lavage, can reduce the severity of symptoms associated with COVID-19. Nasal lavage consists of running salt water in one nostril and out the other to get rid of germs. Saline nasal irrigation with Betadine or baking soda will be evaluated. Participants will be asked to do several things during this study: watch a one minute video on YouTube, use a nasal irrigation device twice a day for 14 days, complete a one-time detailed survey and keep a research diary about their usage and symptoms using an on-line application called Qualtrics, agree to be texted reminders, be called on the phone if they fail to complete the daily diary two days in a row, agree to be called four times, and provide contact information for a secondary person who can be contacted if the primary participant is unavailable. Participation in this study does not involve any significant risks. However, some people may find using nasal irrigation causes them some discomfort. While there are no known benefits to participating in the study participants may see a reduction in their symptoms more quickly than if they didn't participate in the study. ;

Related Conditions & MeSH terms

• COVID-19
• Covid19

• NCT number: NCT04559035
• Study type: Interventional
• Source: Augusta University
• Status: Completed
• Phase: N/A
• Start date: September 24, 2020
• Completion date: November 4, 2021