Clinical Trials Logo

Clinical Trial Summary

Increased risk of osteoarthritis (OA) has been previously demonstrated in patients with lower limb amputation. Although there are many studies on knee joint of intact limb of amputees in the literature, the number of studies on intact foot and ankle is extremely limited. The primary aim of the study is to compare the intact talar cartilage, tibialis anterior and gastrocnemius muscle thickness measurements of traumatic unilateral transtibial amputee patients with that of healthy individuals using ultrasound. The secondary aim is to investigate the relationship between cartilage and muscle thickness measurements with clinical parameters.


Clinical Trial Description

Methods: A total of 36 patients with unilateral transtibial amputations and 36 age and body mass index (BMI)-matched male controls will be participated in this cross-sectional study. Functional performance will be assessed by 6-minute walking distance (in meter). The Foot and Ankle Outcome Score (FAOS) will be used for the assessment of the symptoms and the functional limitations of the foot and ankle. The health-related quality of life of the subjects will be evaluated with Short Form-36 (SF-36). Subjects' talar cartilage, tibialis anterior and gastrocnemius muscle thickness measurements will be performed using musculoskeletal ultrasound. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04486534
Study type Observational
Source Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Contact
Status Completed
Phase
Start date July 26, 2020
Completion date January 15, 2021

See also
  Status Clinical Trial Phase
Completed NCT05999266 - The Cartilage and Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis
Completed NCT03850080 - Autologous Conditioned Serum: Functional and Clinical Results Phase 2/Phase 3
Withdrawn NCT03648463 - Use of MRI Labeling Technique to Track Mesenchymal Stem Cell Survival in Orthopaedic Conditions N/A
Recruiting NCT03477942 - Impact of Mesenchymal Stem Cells in Knee Osteoarthritis Phase 1
Recruiting NCT03955497 - Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury Phase 1/Phase 2
Active, not recruiting NCT05865899 - Impact of High Tibial Osteotomy in Preventing Degenerative Disease Progression in Medial Knee Osteoarthritis. N/A
Completed NCT03072147 - Teriparatide as a Chondroregenerative Therapy in OA Phase 2
Recruiting NCT04310852 - Knee Osteoarthritis Treatment With Percutaneous Injections of Autologous Bone Marrow Concentrate
Completed NCT04454164 - Platelet Rich Plasma Injection for Knee Osteoarthritis Early Phase 1
Recruiting NCT06368544 - Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction N/A
Recruiting NCT03790189 - Subchondral and Intra-articular Application of Bone Marrow Concentrate for Knee Unicompartmental OA N/A
Completed NCT01418755 - Study of Platelet-rich Plasma in Treating Patients With Tibiofemoral Cartilage Degeneration N/A
Recruiting NCT06249906 - Efficacy of Bioceramic Materials for Bone Defects Repair N/A
Not yet recruiting NCT04968665 - The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
Recruiting NCT04536103 - Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry