Wound With Foreign Body (With or Without Infection) Clinical Trial
Official title:
Professor and HOD Department of Surgery DIMC
Patient diagnosed with Para umbilical hernia, umbilical hernia, epigastric will be selected for the study. Sampling technique will be systematic with every 2nd patient being exposed to Gentamycin spray during mesh repair. . Each procedure took 90 to 120 minutes approximately. All patients underwent open abdominal hernioplasty operated on elective list. After placing onlay polypropylene mesh fixed with 2-0 prolene and gentamicin 160 mg injection will be sprayed over the secured mesh. Close active suction drain will be placed in subcutaneous space. Finally we will close the skin with Prolene 2-0 with vertical mattress suture or stapler.
Patients and methods:
The study will be conducted at Dow University Hospital Karachi, Ojha Campusa. The subjects
included were elective patients operated for abdominal hernias. Sample size calculated for a
larger study with 50% frequency, and 99% confidence levels, using Openepi was found to be
664. According to Connelly*, the sample size of pilot study should be 10% of the sample size
of a larger pilot study. As it is a pilot study, the sample size for this study was found to
be 66.
We will take the informed consent before including the patient in the study. Inclusion
criteria Following hernia operated on elective list
- Para umbilical hernia
- Umbilical hernia
- Epigastric hernia
Exclusion criteria
- All above hernia operated in emergency
- Inguinal hernia
Sampling technique will be systematic with every 2nd patient being exposed to Gentamycin
spray during mesh repair. . Each procedure took 90 to 120 minutes approximately. All patients
underwent open abdominal hernioplasty operated on elective list. After placing onlay
polypropylene mesh, fixed with 2-0 prolene and gentamicin 160 mg injection will be sprayed
over the secured mesh. Close active suction drain will be placed in subcutaneous space.
Finally skin will be close with Prolene 2-0 with vertical mattress suture or stapler. All
patients discharge on a day care basis with follow-ups in the OPD Out patient Department for
any post-operative SSI Surgical site infection for a period of two weeks. Drains will be
remove once no or less than 20 ml serosanguinous/ serous discharge in 24 hours.
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