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Clinical Trial Summary

The link between epigenetic changes as an effect of psychotherapy has been investigated recently. Genes investigated in these studies were brain-derived neurotrophic factor (BDNF), NR3C1, FKBP51, MAOA and GLUT1. Change in methylation of these genes could be a biomolecular mechanism of psychotherapy induced changes. This study project aims at providing evidence for a biological mechanism of personality disorder interventions in adolescence by investigating the link between epigenetic changes as an effect of psychotherapy. It investigates the correlation between changes in the methylation of the FKBP5 gene and psychotherapy induced changes in symptoms and functioning.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04095546
Study type Observational
Source University Hospital, Basel, Switzerland
Contact
Status Withdrawn
Phase
Start date April 2022
Completion date December 2024

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