Remineralization Effect of the Varnish on White Spot Lesions Clinical Trial
Official title:
Remineralization Potential of MI Varnish(CPP-ACP and Fluoride) Versus Fluoride Varnish in Controlling White Spot Lesions in Maxillary Primary Incisors: A Randomized Clinical Trial
Remineralization effect of CPP-ACP and Fluoride (MI varnish) versus Fluoride varnish on white spot lesions in maxillary primary incisors
Early childhood caries (ECC) is a very common and consequential chronic disease affecting
young children ( Çolak et al., 2013). The prevalence of ECC in Egypt is high, it is about
(78%) according to the last Egyptian Report, 2014.
ECC begins with white-spot lesions, and caries can progress continuously, leading to complete
destruction of the crown. Calcium and phosphate ions are more readily lost for children
because lower mineralization of deciduous enamel. The disease usually develops very quickly
and causes many childhood health problems, such as caries-related toothache and infection.
Demineralization and remineralization are dynamic processes in caries initiation,
progression, and reversal. Therefore, regulation of the demineralization- remineralization
balance is a key to caries prevention and treatment. The ideal method of increasing
remineralization is reconstructing the depleted tissues with hydroxyapatite, which is the
same inorganic component as the enamel.
Fluoride varnishes have been the standard practice for the professional application of
fluoride.
Casien PhosphoPeptide (CPP) is a sticky protein that binds and stabilizes calcium and
phosphate ions in an amorphous state. CPP-ACP has been shown to adhere to teeth surfaces.
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