The Reliability, Validity, and Responsiveness of the Timed 360° Turn Test in Patients With Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting Clinical Trial

Official title:

The Reliability, Validity, and Responsiveness of the Timed 360° Turn Test Test in Patients With Multiple Sclerosis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03718026
• Other study ID #: 438
• Status: Completed
• Start date: October 24, 2018
• Est. completion date: November 19, 2018

Study information

• Verified date: November 2018
• Source: Gazi University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of the study is to investigate reliability, validity, and responsiveness of the timed 360° turn test in patients with Multiple Sclerosis.

Description:

At baseline, the timed 360° turn test, Berg Balance Scale, Timed Up and Go test, Functional Reach Test, Four Square Step Test, and One-legged Stance Test is applied to the Multiple Sclerosis group. The timed 360° turn test is repeated after seven days from the first application in patients with Multiple Sclerosis. Healthy controls are going to perform only the timed 360° turn test.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 95
• Est. completion date: November 19, 2018
• Est. primary completion date: November 16, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• at least 18 years,

• neurologist-diagnosed Multiple Sclerosis,

• Expanded Disability Status Scale (EDSS) score < 7,

• able to walk 20 m with or without aids,

• no MS exacerbation within the last 2 months,

• use of stable medication in the last 2 months.

Exclusion Criteria:

• other neurologic disorder,

• Pregnancy,

• orhopedic problems affecting gait and stance,

• visual, auditory, orientational problems that could affect study results,

• Cardiovascular, pulmonary, and humoral disease.

Related Conditions & MeSH terms

• Multiple Sclerosis
• Multiple Sclerosis, Relapsing-Remitting
• Sclerosis

Intervention

Other:
• The timed 360° turn test
The timed 360° turn test: Each participant turns around in place in a standing position for both sides. Berg Balance Scale: It has 14 items, each of which is scored from 0 (i.e, severely impaired balance) to 4 (i.e., no balance impairment). Timed Up and Go test: It requires individual to stand up from an armed chair, walk 3m, turn around, walk back to the armed chair, and sit down again. Functional Reach Test: It measures the maximum distance an individual is able to reach forward beyond arm's length in the standing position when maintaining a fixed base of support. One-leg stance test: Individuals were asked to stand on either their left or right leg. Four square step test: It requires an individual to step over obstacles in various directions including forward, backward, and sideways.

Locations

Country	Name	City	State
Turkey	Fatih Söke	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Gazi University

Country where clinical trial is conducted

Turkey, 

References & Publications (4)

Adusumilli G, Lancia S, Levasseur VA, Amblee V, Orchard M, Wagner JM, Naismith RT. Turning is an important marker of balance confidence and walking limitation in persons with multiple sclerosis. PLoS One. 2018 Jun 7;13(6):e0198178. doi: 10.1371/journal.pone.0198178. eCollection 2018. — View Citation

Cameron MH, Asano M, Bourdette D, Finlayson ML. People with multiple sclerosis use many fall prevention strategies but still fall frequently. Arch Phys Med Rehabil. 2013 Aug;94(8):1562-6. doi: 10.1016/j.apmr.2013.01.021. Epub 2013 Feb 4. — View Citation

Gunn H, Creanor S, Haas B, Marsden J, Freeman J. Frequency, characteristics, and consequences of falls in multiple sclerosis: findings from a cohort study. Arch Phys Med Rehabil. 2014 Mar;95(3):538-45. doi: 10.1016/j.apmr.2013.08.244. Epub 2013 Sep 18. — View Citation

Spain RI, St George RJ, Salarian A, Mancini M, Wagner JM, Horak FB, Bourdette D. Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed. Gait Posture. 2012 Apr;35(4):573-8. doi: 10.1016/j.gaitpost.2011.11.026. Epub 2012 Jan 25. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The timed 360° turn test	The timed 360° turn test evaluates turning ability. Higher durations indicate worse turning performance.	1 minute
Secondary	Berg Balance Scale	Berg Balance Scale assesses functional balance. It consists of 14 functional tasks rated on a 5-point scale ranging from 0 to 4. The maximum score is 56 points. Higher scores indicate better functional balance.	10 minutes
Secondary	Timed Up and Go test	Timed Up and Go test evaluates functional mobility. Higher durations indicate worse functional mobility.	1 minute
Secondary	Functional Reach Test	Functional Reach Test is used to evaluate limits of stability. Higher distances indicate better limits of stability.	1 minute
Secondary	Four Square Step Test	Four Square Step Test is used to assess dynamic balance. Higher durations indicate worse dynamic balance.	1 minute
Secondary	One Leg Stance Test	One Leg Stance Test evaluates postural stability. Higher durations indicate better postural stability.	3 minutes