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Clinical Trial Summary

The purpose of this study is to evaluate Omega-3 Wound™ as an alternative to autogenous free gingival grafts harvested from the palate to treat human subjects with insufficient KT (< 2 mm)


Clinical Trial Description

Primary objective:

The primary aim will be to see if Omega-3 Wound™ is clinically superior to tissue harvested from the palate (Autogenous Free Gingival Graft) when comparing before and after measurements of: keratinized tissue. Change in KT width from time of surgery to 6 months post-surgery (22).

Secondary objectives:

1. Measures of periodontal health (probing depth, recession levels, bleeding on probing, plaque score, clinical attachment level, resistance to muscle pull, vestibular depth, healing time) over 3 months (at study entry, 4 weeks, 3 months and 6 months)

2. Time of surgery

3. Subject Discomfort Survey during healing and at 1 week and 4 weeks

4. Subject Preference Questionnaire at month 6

5. Safety endpoints assessed by monitoring adverse events ;


Study Design


Related Conditions & MeSH terms

  • Mucogingival Deformity - Insufficient Keratinized Tissue

NCT number NCT03664401
Study type Interventional
Source Kerecis Ltd.
Contact
Status Completed
Phase Early Phase 1
Start date September 1, 2016
Completion date December 1, 2017