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Clinical Trial Summary

This is a Phase 1 multicenter, single-arm, open-label, dose escalation and dose expansion study of enhancer of zeste homolog 2 (EZH2 ) inhibitor SHR2554. This study will assess the tolerability, safety, pharmacokinetics, and preliminary anti-tumor activity of SHR2554 in participants with relapsed or refractory mature lymphoid neoplasms in part I, and the the efficacy in PTCL patients will be studied in Part II.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03603951
Study type Interventional
Source Jiangsu HengRui Medicine Co., Ltd.
Contact Weiwei Wang, MD
Phone +86-021-68868570
Email weiwei.wang@hengrui.com
Status Recruiting
Phase Phase 1
Start date August 14, 2018
Completion date August 14, 2023