Sedentary Behavior;Cognition;Cardiovascular-related Disease Clinical Trial
Official title:
Prospective Cohort Study on Cognition and Cardiovascular Disease of Sedentary Behaviors in Children
The prospective cohort study is set up to address research questions dealing with sedentary lifestyle-related events mainly including cognition and cardiovascular-related disease in children .Participants aged 7-12 years old from five primary schools in Guangzhou,Guangdong province will be recruited and followed up to evaluate the risk factors of cognition and cardiovascular-related disease. Objective measurements combined with questionnaire-data-based information on a wide range of lifestyle factors and cognition were applied in this study.
There are three stages in this project.At first stage,information about socio-demographic,
psychological status, physical activity,sleep and diet were collected by a multi-components
questionnaire survey.The Strengths and Difficulties Questionnaire(SDQ) and Behavior Rating
Inventory of Executive Function(BRIEF) were conducted at the same time. Anthropometric
measurement including height, weight, waist and hip circumferences, blood pressure and fat
mass were conducted.Besides,blood samples were collected to measure total cholesterol,
triglycerides, high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C).
At second stage,participants were classified for 4 subgroups as follows: Low active-high
sedentary;low active-low sedentary; high active-high sedentary;high active-low sedentary by
different sedentary status and physical activity levels according to the international
standard. Later cardiorespiratory fitness was assessed by the 20-m shuttle run test.
Accelerometer GT3X+ Actigraph with physical activity log,Combined Raven's test, a series of
psychometric paradigms were measured for further studies.
At third stage,we will explore the related neuropsychological mechanism using the technology
of event-related potentials (ERPs).
About 1000 participants (7-12 years old) will be prospectively followed up. The associations
between sedentary lifestyle and risks for cognition and cardiovascular-related disease will
be evaluated.
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