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Comarum Palustre in Knee Osteoarthritis and Diabetes

Diabetes Mellitus Clinical Trial

Official title:
Analgesic, Antiinflammatory and Metabolic Effects of Comarum Palustre in Patients With Osteoarthritis and Diabetes Mellitus

Clinical Trial Summary

The study evaluates analgesic, antiinflammatory and metabolic effects of Comarum palustre in patients with knee osteoarthritis (OA) and diabetes mellitus. Patients with osteoarthritis will receive Comarum palustre together with conventional treatment of osteoarthritis and diabetes.

Clinical Trial Description

Comarum palustre have been shown to exert analgesic properties in patients with knee osteoarthritis not responding to diclofenac. In animal models comarum palustre showed anti-inflammatory, immunomodulatory, analgesic, antioxidant, antihistamine, and membrane-stabilizing effects. Thus, pleiotropic properties of Comarum Palustre may provide a rationale for this use in patients having both osteoarthritis and diabetes mellitus. In this group of patients Comarum Palustre may not only relieve OA-related pain but reduce systemic inflammation, decrease progression of atherosclerosis and diabetes complications. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03530930
Study type Interventional
Source Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology
Contact
Status Completed
Phase Phase 4
Start date June 29, 2018
Completion date November 25, 2018
View Details
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