Elective Craniotomy-candidated Patients Clinical Trial
Official title:
The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy
Surgical-site infection is the most commonly reported nosocomial infection in patients
undergoing surgery and 3rd most nosocomial infection in hospitalized patients. The SSI is
associated with increases of length of hospitalization for 6 days and increases the
hospital's cost by $ 300.
Because of these, prevention of SSI with appropriate antibiotic is essential.
| Status | Not yet recruiting |
| Enrollment | 126 |
| Est. completion date | August 1, 2019 |
| Est. primary completion date | April 1, 2019 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - age 18 years and above - elective surgical patients - No pre-surgery infection - Do not use antibiotics before surgery - Insensitivity to beta-lactam antibiotics Exclusion Criteria: - cranioplasty - Failure to follow the patient - The patient's unwillingness to continue participating in the research project - Death of the patient |
| Country | Name | City | State |
|---|---|---|---|
| Iran, Islamic Republic of | Isfahan university of medical science. | Isfahan |
| Lead Sponsor | Collaborator |
|---|---|
| Isfahan University of Medical Sciences |
Iran, Islamic Republic of,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | infection rate | compare of infection rate in 2 groups | Until 90 days after admission | |
| Secondary | length of hospitalization | compare the length of hospitalization in 2 groups | Until 90 days after admission | |
| Secondary | raise of ESR & CRP | compare the raise of ESR & CRP in 2 groups | Until 90 days after admission |