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Clinical Trial Summary

The purpose of this study is to confirm the safety and efficacy of Apatinib in Combination With Radiotherapy / Chemotherapy for Second-line and Above Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma.


Clinical Trial Description

Head and neck cancer refers to the skull base to the supraclavicular, cervical spine within the scope of all malignant tumors is more common in China's malignant tumors. Head and neck cancer mainly surgery and radiotherapy, chemotherapy alone or in combination therapy, common head and neck squamous cell carcinoma chemotherapy programs are: PF regimen (cisplatin + 5-fluorouracil), PLF program (cisplatin + carboplatin +5 - fluorouracil), TPF program (cisplatin + 5 - fluorouracil + paclitaxel) and so on. The researcher consider to add apatinib,a tyrosine kinase inhibitor of VEGF,to the therapy of these patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03424291
Study type Interventional
Source Henan Cancer Hospital
Contact hui Wu
Phone 13503716710
Email wuhui7008@126.com
Status Recruiting
Phase Phase 2
Start date July 5, 2017
Completion date July 2019

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