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Clinical Trial Summary

The pathophysiology of primary immunodeficiencies (PID), which encompass a broad range of different diseases with susceptibility to infection and/or a deregulated inflammatory response, is poorly understood. Available treatments are often not specific for a distinct target and might be associated with side effects. To elucidate pathophysiology of different PIDs, stool, urine, blood, tissue biopsies and/or bone marrow will be collected and analysed for anti-microbial activity and inflammatory response. In a second step, targeted treatment for different PIDs might be developed preclinically and ex vivo according to underlying pathophysiology.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03422614
Study type Observational
Source University of Zurich
Contact Janine Reichenbach, Prof. Dr.
Phone +41442667311
Email janine.reichenbach@kispi.uzh.ch
Status Recruiting
Phase N/A
Start date July 1, 2015
Completion date July 1, 2025

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