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Clinical Trial Summary

This study evaluates the addition of a mouth rinse containing sea salt, xylitol and lysozyme to standardized oral health practices on biofilm formation and gingival health in a group of young adults.


Clinical Trial Description

The purpose of this study is to evaluate a new sea salt mouth rinse containing xylitol and the antibacterial enzyme, lysozyme on biofilm formation and gingival health in a group of young adults. Xylitol is a well-established non-sugar sweetener and an anti-caries agent. The use of this polyol results in loosely adherent biofilms by reducing the amount of extracellular lipopolysaccharides and lipoteichoic acids, facilitating its easy removal by mechanical means. Lysozymes are antibacterial proteins that hydrolyze the linkage between N-acetylmuramic acid and N-acetylglucosamine of peptidoglycan in the cell wall of Gram + bacteria effectively limiting growth. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03329105
Study type Interventional
Source University of Saskatchewan
Contact
Status Completed
Phase N/A
Start date November 7, 2016
Completion date August 24, 2017

See also
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Completed NCT04767269 - Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis. Phase 2/Phase 3
Completed NCT02861937 - Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels N/A